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Virology Innovations by Harati Adhikari

As a growing field, Virology has prompted many new innovations in order to make people’s lives easier when it comes to dealing with viruses. From the development of vaccines to AI technology, such innovations have helped to advance the field for further research, experimentation, and medicine. In this article, I will be talking about the many innovations that have helped advance the field of virology in the medical field and how it has contributed to the world of advanced medicine.

  1. Vaccine Development: Vaccines are probably the biggest innovations that the field of virology has done; combating life-threatening illnesses and diseases with a formulated solution filled with molecules that’s injected in your arm, targeting not the virus, but the cells. Vaccine development is a long process, in fact, taking years to formulate when a new virus is introduced. However, with new technology and tons and tons of money, such processes become a lot more simpler. Inorder to create a vaccine, Researchers use a variety of methods to develop vaccines, such as using weakened or inactivated viruses. The harmful parts of the virus are extracted, however, this is so that if the virus does come in contact with the body, the body is able to recognize it and be able to effectively fight against it. With such research, more vaccines are able to be researched and be created for use by millions of people to protect themselves, for example the Covid-19 vaccine. In fact, even after the first 2 doses, advanced research and technology has allowed for more vaccines to form inorder to strengthen our immune system and help everyone be healthy and safe from harmful diseases.

  2. Gene editing technology: Gene editing technology is an area of virology that has allowed scientists to modify genetic material of living cells. One of the most prominent techniques of gene-editing technology is CRISPR-Cas, a technique that allows scientists to cut DNA at specific sites and replace or remove sections of genetic material. It is mostly used in gene-modification, where geneticists and researchers introduce changes in specific places in the genome, by removing or adding either whole genes or single bases. However, this technology also has many applications in virology research. Researchers use this technique to modify specific genes that are essential for viral replication, in order to prevent the virus from spreading itself to other host cells that attack the body. This technology is a rapidly growing area of research in medicine, however, it has also found its place in virology as well. We can expect to see potential for developing new antiviral therapies and improving ways to approach viral infections with such technology.

  3. Anti-virals: Antivirals are medications that can be used to treat viral infections by helping stop the virus from multiplying, helping to reduce the severity of an infection, speed up recovery time, and even prevent it from spreading to other people while being infected. Though these are not complete cures for viral illnesses, they do help relieve the pain and affects a virus can bring.

Some antivirals work by inhibiting the enzymes required for viral replication, while others interfere with viral formation. Here are some examples of antiviral medications:

  • Acyclovir: An antiviral used to treat herpes simplex and varicella-zoster virus infections

  • Oseltamivir: An antiviral used to prevent and treat influenza infections

  • Sofosbuvir: An antiviral used to treat hepatitis C virus infections

  • Zidovudine: An antiviral used to treat HIV infections

In recent years, there have been significant breakthroughs in the development of antiviral drugs, especially for hepatitis C and HIV infections.

As viruses continue to evolve and become resistant to medication, there is a need for continued research being conducted on antiviral drugs. In fact, there were antivirals created during the covid-19 pandemic, such as axlovid, Lagevrio, and Veklury. Each had their own criteria, benefits, requirements, and side-effects that were meant to help the public become more immune to the virus, even if vaccines weren’t able to be discovered.

  1. AI and Machine Learning: AI, or artificial Intelligence, and machine learning are innovative technologies that have helped the study of virology, among other areas. In virology, AI and machine learning techniques have been applied in various ways. These techniques are used to analyze large amounts of viral data, identify patterns and develop new treatments. Here are some examples of how AI and machine learning are used in virology:

  • Drug discovery: Machine learning and AI can help identify potential drugs and compounds for antiviral drugs. In fact, Machine learning algorithms are able to scan millions of molecules to identify antiviral properties by looking at their structure or finding its resemblance to different proteins.

  • Diagnostics: AI and machine learning models have been developed to rapidly and accurately diagnose viral infections. These models are capable of identifying specific viruses and providing a quick diagnosis for a disease.

  • Epidemiological research: Important role in analyzing epidemiological data when it comes to viral diseases. Machine learning models can analyze trends in disease outbreaks and predict risk of new outbreaks. Models can also identify patterns of transmission based on many data points or occurrences.

Machine learning and AI technologies can be used to analyze the patient's genetic information as well as environmental factors to offer a personalized prescription for treatment to suit their requirements and increase efficiency.


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